Computational Approaches to Large-scale/Complex Nuclear Reactor Analysis

JOSHUA—A Nuclear Reactor Design and Analysis Computational System

JOSHUA is a computational system developed to perform the extensive engineering and physics calculations needed in the design and analysis of Savannah River Plant (SRP) nuclear reactors. Application of this system significantly enhanced the efficiency, effectiveness, accuracy, and safety of nuclear reactor design and analysis. The unique features of SRP reactors, which necessitated the Site’s d...

Computational Fluid Dynamics for Nuclear Reactor Safety-5 (CFD4NRS-5)

Computational approaches to neuronal network analysis.

Computational modelling is an approach to neuronal network analysis that can complement experimental approaches. Construction of useful neuron and network models is often complicated by a variety of factors and unknowns, most notably the considerable variability of cellular and synaptic properties and electrical activity characteristics found even in relatively 'simple' networks of identifiable...

Computational Approaches to Ancient Genome Analysis

Recent advancements in sequencing technologies have made it possible to sequence large quantities of the DNA preserved in ancient remains. This DNA differs from modern DNA in three key aspects. First, the DNA is fragmented into short molecules. Second, the DNA is damaged leading to misreads bases during sequencing. Last, molecules from the ancient species are mixed with molecules from microbial...

Computational approaches to psychiatry.

A major reason for disappointing progress of psychiatric diagnostics and nosology is the lack of tests which enable mechanistic inference on disease processes within individual patients. The resulting inability to pursue formal differential diagnosis has forced the field to stick to symptom-based diagnostic schemes with limited predictive validity concerning treatment response and clinical outc...